Study of the Effects of HIRREM on Stage One Primary Hypertension

What we are studying

HIRREM is a computer-based technology that may help improve your blood pressure by using auditory tones that are played back based on readings of your brain’s electrical frequencies, to support a shift towards a more balanced pattern. Adults, age 18 and above, who have documented blood pressures that place them in the category of Stage 1 hypertension (systolic BP 130-139, and/or diastolic BP 80-89), who have no other identifiable cause for hypertension are eligible to participate in the study.

Who is Eligible

  • All Genders
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 18+

Eligibility Criteria

  • Must be able to provide informed consent
  • Must be physically able to come to the study visits or to sit comfortably in a chair for up to two hours at a time
  • Must weigh less or equal to chair limit (285 pounds)
  • Not diagnosed with atherosclerotic cardiovascular disease
  • Does not have cardiovascular risk score of greater than or equal to 10%
  • Not diagnosed with stage 2 hypertension
  • No ongoing need for treatment of hypertension with medications
  • Not diagnosed with any seizure disorder
  • Not pregnant
  • No severe hearing impairment (because the subject will be using headphones during the interventions)
  • No ongoing need for treatment with opiate; benzodiazepine; anti-psychotic medications; anti-depressant medications (SSRI; SNRI; tricyclic); or sleep medications (zolpidem; eszopiclone)
  • No anticipated and ongoing use of recreational drugs; alcohol; or energy drinks
  • No ongoing need for treatment with thyroid medications
  • Not enrolled in another research study that includes an active intervention
  • Have not received brainwave optimization (BWO); used a B2 or B2v2 wearable device; or previously participated in a HIRREM research study

What is involved

  • Four study visits
  • Eight to 16 sessions (90-120 minutes each) listening to sounds while relaxing in a chair


You will be paid $100 compensation for time, travel, and inconvenience related to study visits, if you complete the study. If you do not complete the study, you will paid $25 per visit for each completed visit.

Contact Information

Study Coordinator
Krystal Schmidt

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.