Therapeutic Effects of Exercise in Adults with Mild Memory Impairment

What we are studying

Exercise programs may improve memory and thinking abilities for adults with mild memory loss. The purpose of this research study is to examine the effects of stretching, balance, and range of motion exercise versus moderate-to-high-intensity aerobic exercise on memory and thinking skills. We will recruit up to 30 people between 65 and 89 years of age who are having difficulty with memory and thinking.

Who is Eligible

  • Genders:
    • Men
    • Women
  • Races:
    • White
    • African American
    • Asian
    • American Indian or Alaska Native
    • Native Hawaiian or Pacific Islander
    • Other
  • All Ethnicities
  • Ages 65 - 89

Eligibility Criteria

  • Diagnosis of amnestic MCI
  • Fluent in English
  • Hearing and vision is adequate to complete study exams
  • Study partner willing to attend clinic visits
  • Sedentary or inactive
  • Willing to participate in either study group
  • Willing to attend study sessions at a YMCA 4 times per week for 18 months

What is involved

  • Attend up to 7 clinic visits over the next 20 months
  • Attend exercise group 4 times per week for 18 months
  • Give blood samples up to 5 times
  • Have physical & neurological exams
  • Take tests of memory and thinking
  • Have an EKG
  • Complete a short walking test
  • Have 2 MRI scans and 2 lumbar punctures


Screening Visit: $25. Screening MRI Scan: $25. Baseline Visit: $100. Month 6: $25. Month 12: $150. Month 18: $25.

Contact Information

Study Coordinator
Tim Collare
Principal Investigator
Laura Baker, PhD

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.